Mechanisms of Myocardial Stunning in Stress-Induced Cardiomyopathy
نویسندگان
چکیده
Stress-induced cardiomyopathy, in contrast to acute myocardial infarction, is a type of heart failure characterized by reversible left ventricular dysfunction. Cardiac imaging primarily reveals ventricle stunning, 81.7% which apical type. Emotional or psychological stress usually precedes the onset stress-induced increasingly being recognized as unique neurogenic stunning disease. To distinguish between infarction and viral auto-immune myocarditis, this review summarizes specific mechanisms such calcium disorders, metabolic alterations, anatomical histological variations different parts ventricle, microvascular
منابع مشابه
Molecular and cellular mechanisms of myocardial stunning.
The past two decades have witnessed an explosive growth of knowledge regarding postischemic myocardial dysfunction or myocardial "stunning." The purpose of this review is to summarize current information regarding the pathophysiology and pathogenesis of this phenomenon. Myocardial stunning should not be regarded as a single entity but rather as a "syndrome" that has been observed in a wide vari...
متن کاملCellular and extracellular mechanisms causing myocardial stunning.
Myocardial stunning involves a profound and slowly recovering decrease in contractility that follows a brief but severe episode of ischemia (1). A report in this issue of the Journal of the American College of Cardiology (2) challenges the prevailing view that the mechanisms underlying stunning are cellular in origin. Interestingly, Chandrashekhar et al. (2) found there was little difference in...
متن کاملMechanisms of Myocardial Ischemia in Hypertrophic Cardiomyopathy
BACKGROUND Angina is common in hypertrophic cardiomyopathy (HCM) and is associated with abnormal myocardial perfusion. Wave intensity analysis improves the understanding of the mechanics of myocardial ischemia. OBJECTIVES Wave intensity analysis was used to describe the mechanisms underlying perfusion abnormalities in patients with HCM. METHODS Simultaneous pressure and flow were measured i...
متن کاملMyocardial Stunning in Dogs
This study was undertaken to elucidate whether cal-adrenoceptor activity is beneficial to contractile dysfunction during reperfusion after a brief period of ischemia (stunned myocardium) in 54 open-chest dogs. Contractile dysfunction assessed by fractional shortening (FS) was observed 3 hours after the onset of reperfusion following 15 minutes of complete occlusion of the left anterior descendi...
متن کاملMechanism of myocardial "stunning".
Among the numerous mechanisms proposed for myocardial stunning, three appear to be more plausible: 1) generation of oxygen radicals, 2) calcium overload, and 3) excitation-contraction uncoupling. First, the evidence for a pathogenetic role of oxygen-derived free radicals in myocardial stunning is overwhelming. In the setting of a single 15-minute coronary occlusion, mitigation of stunning by an...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cardiovascular innovations and applications
سال: 2022
ISSN: ['2009-8782', '2009-8618']
DOI: https://doi.org/10.15212/cvia.2022.0010